A infects Human ,Mammals and birds.But B & C types are isolated only to Humans. C types are not epidemics. They mainly infect Human,Pigs,Horses as well as birds.It is spherical inj shape of 80-120nm in diameter but sometime may be the length of several micrometers. It has got helical nucleocapsid comprising
8 segmernts. There are two types of spike projected from the envelope.Hemagglutinin(H) and Neuraminidase(N).Hemagglutinin(H) can attach to host sialic acid recepturs.The Sialic acid receptors are present on the surface of erythrocytes, So virus with HA glycoprotein cause hema-agglutination .When mixed with red blood cells.(mainly atack Respiratory track). Host cell sialic acid receptor also exist on upper respiration track cell membranes and HA binding to these receptors activates fusion of the host cell membrane with Virion Membrane,resulting in viral genome entry into cells.Neuramic acid is an important component of mucin,those
substance covering mucosal epithelial cells are forming an integral part of the hosts upper respiration Defense barrier.
symptoms:
1. High fever
2. Muscleaches
3. Extreme drowsiness
Treatmant and control
1.Drugs:Amantadine prevents the uncoating of influenza A.This medicine prevent from infection if given daily before exposure or it decrease the severity of the Illness so is given in early course.
2.Vaccine: A vaccine consists of formalin which are available.Due to this reason High Risk group are free from Chromic Pulmonaryor cendiac Diseases.
No comments:
Post a Comment